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pentobarbital will decrease the extent or result of fostemsavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will reduce the extent or influence of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Lack of, or lessened response to tofacitinib might happen when coa